Controloc: Treatment with Controloc can occasionally lead to headache, gastrointestinal complaints eg, upper abdominal pain, diarrhea, constipation or flatulence and allergic reactions eg, pruritus, skin rash (in isolated cases also urticaria or angioedema).
There have been rare reports of nausea, dizziness or disturbances in vision (blurred vision). Peripheral edema, fever, depression or myalgia subsiding after termination of therapy were reported in individual cases.
Ospamox: Occasional transient adverse effects are mostly gastrointestinal (nausea and diarrhea). Owing to the better absorption of amoxicillin, they are, however less commonly seen than during ampicillin treatment. In patients developing diarrhea during treatment, pseudomembranous colitis should be considered (see Precautions). Rarely, hypersensitivity reactions eg, urticarial rashes, fever, joint pain, erythema multiforme, exfoliative dermatitis, angioneurotic edema and hematologic problems eg, thrombocytopenia, agranulocytosis, leukopenia and eosinophilia are seen. These usually run a mild course and generally subside within a few days. Like other penicillins, Ospamox may exceptionally cause severe systemic reactions (anaphylactic shock). Exfoliative dermatitis and erythema multiforme have been described in some cases. Like other penicillins, amoxicillin may cause headache, fatigue, glossitis, stomatitis, fever, joint pain, angioneurotic edema or interstitial nephritis. Minor transient elevations of serum transaminases (SGOT and SGPT) have occasionally been seen.
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